AnaesthesiaUK Journal

Treatments for neuropathic pain differentially affect delayed matching accuracy by macaques: effects of amitriptyline and gabapentin

Mon, 08 Mar 2010 00:00:00 GMT

H3 PCurrent clinical treatments for neuropathic pain include amitriptyline and gabapentin. Since few assessments of cognitive performance have been made in non-human primates with these marketed treatments, these authors aimed to determine their relative abilities to alter working memory, as measured in mature macaques in their performance of a delayed ......
Pain - Pain 2010; 148: 446-53
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Dexamethasone with bupivacaine increases duration of analgesia in ultrasound-guided interscalene brachial plexus blockade

Mon, 08 Mar 2010 00:00:00 GMT

H3 PThe purpose of this study was to determine whether the addition of dexamethasone to interscalene achial plexus block would prolong the duration of sensory analgesia in patients undergoing outpatient shoulder arthroscopy. BRP H3Methods H3 PThe authors carried out a prospective, randomised, double-blind investigation in 88 individuals undergoing shoulder arthroscopy. Patients received ......
Pain - Eur J Anaesthesiol 2010; 27: 285-8
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Obstetric epidural catheter-related infections at a major teaching hospital: a retrospective case series

Mon, 08 Mar 2010 00:00:00 GMT

H3 PClinically overt infections of the epidural catheter skin entry site occur in approximately 1-5% of patients after a few days of catheterisation. Although serious complications, such as deep tissue infection or epidural abscess, are thought to be rare in the obstetric population, recent sporadic reports and small series suggest ......
Obstetrics - Int J Obstet Anesth 2010; 19: 38-43
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Minimum effective bolus dose of oxytocin during elective Caesarean delivery

Mon, 08 Mar 2010 00:00:00 GMT

H3 PThese authors aimed to determine the lowest effective bolus dose of oxytocin to produce adequate uterine tone (UT) during elective Caesarean delivery (CD). BRP H3Methods H3 PA total of 75 pregnant patients undergoing elective CD under spinal anaesthesia were randomised to receive oxytocin (0.5, 1, 3, 5 units) or placebo. UT ......
Obstetrics - Br J Anaesth 2010; 104: 338-43
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Comparison of dopamine and norepinephrine in the treatment of shock

Mon, 08 Mar 2010 00:00:00 GMT

H3 PThe authors carried out a study to compare the efficacy of dopamine and norepinephrine as first-line vasopressor agents in the treatment of shock BRP H3MethodsH3 PIn a multicentre, randomised trial, the authors assigned 1679 patients with shock to receive either dopamine (n=858) or norepinephrine (n=821) as first-line vasopressor therapy to restore ......
Intensive Care - N Engl J Med 362:779-89
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Therapeutic hypothermia after cardiac arrest - implementation in UK intensive care units

Mon, 08 Mar 2010 00:00:00 GMT

H3 PThe authors carried out a telephone survey to determine how many UK intensive care units were using therapeutic hypothermia as part of their management of unconscious patients admitted after cardiac arrest. BRP H3MethodsH3 PThe authors contacted all 247 intensive care units listed in the 2008 Directory of Critical Care Services to ......
Intensive Care - Anaesthesia 2010 Jan 18. [Epub ahead of print]
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The effect of bispectral index monitoring on long-term survival in the B-aware trial

Mon, 08 Mar 2010 00:00:00 GMT

H3 PWhen anaesthesia is titrated using bispectral index (BIS) monitoring, patients generally receive lower doses of hypnotic drugs. Intraoperative hypotension and organ toxicity might be avoided if lower doses of anaesthetics are administered, but it has not been established whether this leads to a reduction in serious morbidity or mortality. ......
Anaesthesia - Anesth Analg 2010; 110: 816-22
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To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial

Mon, 08 Mar 2010 00:00:00 GMT

H3 PMajor adverse cardiac events (MACEs) are a common cause of death after non-cardiac surgery. These authors carried out a randomised, double-blind, placebo-controlled trial in order to compare the effect of low-dose aspirin with that of placebo on myocardial damage, and cardiovascular and bleeding complications in high-risk patients undergoing non-cardiac ......
Anaesthesia - Br J Anaesth 2010; 104: 305-12
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Continuous peripheral nerve blocks: is local anesthetic dose the only factor, or do concentration and volume influence infusion effects as well?

Thu, 11 Feb 2010 00:00:00 GMT

authors investigated whether the main determinant of continuous peripheral nerve block effects is local anesthetic concentration and volume or simply total drug dose. BRP H3Methods H3 PThe authors compared two different concentrations and basal rates of ropivacaine - but at equivalent total doses - for continuous posterior lumbar plexus blocks after ......
Pain - Anesthesiology 2010; 112: 347-54
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Long-term treatment of neuropathic pain with a 5% lidocaine medicated plaster

Thu, 11 Feb 2010 00:00:00 GMT

H3 PThese authors examined the efficacy and tolerability of long-term treatment with the 5% lidocaine medicated plaster in patients with localised neuropathic pain conditions. BRP H3Methods H3 PTwenty patients with localised neuropathic pain (postoperative neuropathic pain [n=14]; complex regional pain syndrome [n=2]; and post-herpetic neuralgia [n=4]), who had been successfully treated with ......
Pain - Eur J Anaesthesiol 2010; 27: 169-73
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