AnaesthesiaUK Journal

Day-surgery patients anesthetized with propofol have less postoperative pain than those anesthetized with sevoflurane

Wed, 07 Jul 2010 00:00:00 GMT

H3 PRecent studies have suggested that patients anesthetised with propofol have less postoperative pain compared with those anesthetised with volatile anaesthetics. BRBRP H3 H3 H3MethodsH3 PThese authors carried out a randomised, double-blind study, in which 80 patients undergoing day-case diagnostic laparoscopic gynaecological surgery were anaesthetised with either intravenous propofol or sevoflurane. The primary outcome ......
Pain - Anesth Analg 2010; 111: 83-5
view abstract

Interpleural analgesia for attenuation of postoperative pain after hepatic resection

Wed, 07 Jul 2010 00:00:00 GMT

H3 PThese authors carried out a prospective, randomised trial to evaluate the analgesic efficacy of interpleural analgesia in patients undergoing hepatic resection. P H3MethodsH3 BRThe control group (n=25) received multimodal analgesia with intravenous morphine patient-controlled analgesia; in addition, the interventional group (n=25) received interpleural analgesia with a 20 ml loading dose ......
Pain - Anaesthesia 2010 Jun 2. [Epub ahead of print]
view abstract

A randomised study of magnesium sulphate as an adjuvant to intrathecal bupivacaine in patients with mild preeclampsia undergoing Caesarean section

Wed, 07 Jul 2010 00:00:00 GMT

magnesium, an NMDA antagonist, has been shown to prolong analgesia following Caesarean section without significant side effects in healthy parturients. The authors therefore studied the effect of adding intrathecal magnesium sulphate to bupivacaine-fentanyl spinal anaesthesia in patients with mild preeclampsia undergoing Caesarean section. BRBRP H3MethodsH3 PA total of 60 women with ......
Obstetrics - Int J Obstet Anesth 2010; 19: 161-6.
view abstract

Rapid sequence spinal anaesthesia for category-1 urgency caesarean section: a case series

Wed, 07 Jul 2010 00:00:00 GMT

and methodsH3 PGeneral anaesthesia in category-1 Caesarean section is associated with increased maternal morbidity and mortality. This paper describes the 'rapid sequence spinal' to minimise anaesthetic time. This consists of a no-touch spinal technique, consideration of omission of the spinal opioid, limiting spinal attempts, allowing the start of surgery before ......
Obstetrics - Anaesthesia 65: 664-9
view abstract

Inhaled carbon monoxide prevents acute kidney injury in pigs after cardiopulmonary bypass by inducing a heat shock response

Wed, 07 Jul 2010 00:00:00 GMT

BRCardiopulmonary bypass (CPB) might be associated with acute kidney injury (AKI). Inhaled carbon monoxide (CO) is cyto- and organ-protective. The authors hypothesised that pretreatment with inhaled CO prevents CPB-associated AKI. BR H3 H3 H3Methods H3Pigs (n=38) were non-randomly assigned to SHAM, standard CPB, pretreatment with inhaled CO (250 parts per million, 1 ......
Intensive Care - Anesth Analg 2010; 111: 29-37
view abstract

Inhaled hydrogen sulfide protects against ventilator-induced lung injury

Wed, 07 Jul 2010 00:00:00 GMT

H3 PMechanical ventilation causes a high rate of morbidity and mortality because of ventilator-induced lung injury (VILI). Therefore, new therapeutic strategies are needed to treat VILI. Hydrogen sulphide can induce hypothermia and suspended animation-like states in mice, as well as anti-inflammatory and antiapoptotic effects. These authors investigated the organ-protective effects ......
Intensive Care - Anesthesiology 2010; 113: 104-15.
view abstract

Hypercapnic acidosis reduces oxidative reactions in endotoxin-induced lung injury

Wed, 07 Jul 2010 00:00:00 GMT

H3 PHypercapnic acidosis, in the absence of any change in tidal volume or airway pressure, is protective when instituted before the onset of injury. These authors investigated the mechanisms by which hypercapnic acidosis confers this protection in vivo, particularly its effects on pulmonary oxidative reactions, which are potent mediators of ......
Intensive Care - Anesthesiology 2010; 113: 116-25
view abstract

A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation

Wed, 07 Jul 2010 00:00:00 GMT

H3 PThe authors aimed to compare the effects of dexmedetomidine versus midazolam on perioperative haemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy. P H3Methods H3A total of 60 ASA I-II patients, between 20 and 80 years of age were included in the study and randomly assigned to two groups. Midazolam ......
Anaesthesia - Eur J Anaesthesiol 2010; 27: 648-52
view abstract

Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry

Wed, 07 Jul 2010 00:00:00 GMT

H3 PHypothermia and acidosis lead to an impairment of coagulation. Desmopressin has been shown to improve platelet function under hypothermia. These authors tested platelet function ex vivo during hypothermia and acidosis. BRBRP H3Methods H3 PBlood samples were taken from 12 healthy subjects and assigned as follows: normal pH, pH 7.2, and pH ......
Anaesthesia - Anaesthesia 2010; May 11. [Epub ahead of print]
view abstract

Clinical characteristics and outcomes of patients with obstructive sleep apnoea requiring intensive care

Thu, 03 Jun 2010 00:00:00 GMT

H3 PThe authors reviewed the clinical characteristics, required intervention and short- and long-term outcomes in obstructive sleep apnoea (OSA) patients requiring intensive care. BRBRP H3MethodsH3 PA retrospective, single-centre, observational cohort study was carried out in a multidisciplinary teaching medical and surgical intensive care unit. Adult patients with OSA (apnoea-hypopnoea index of 5 ......
Intensive Care - Anaesth Intensive Care 2010; 38(3)
view abstract