AnaesthesiaUK Journal

Continuous peripheral nerve blocks: is local anesthetic dose the only factor, or do concentration and volume influence infusion effects as well?

Thu, 11 Feb 2010 00:00:00 GMT

authors investigated whether the main determinant of continuous peripheral nerve block effects is local anesthetic concentration and volume or simply total drug dose. BRP H3Methods H3 PThe authors compared two different concentrations and basal rates of ropivacaine - but at equivalent total doses - for continuous posterior lumbar plexus blocks after ......
Pain - Anesthesiology 2010; 112: 347-54
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Long-term treatment of neuropathic pain with a 5% lidocaine medicated plaster

Thu, 11 Feb 2010 00:00:00 GMT

H3 PThese authors examined the efficacy and tolerability of long-term treatment with the 5% lidocaine medicated plaster in patients with localised neuropathic pain conditions. BRP H3Methods H3 PTwenty patients with localised neuropathic pain (postoperative neuropathic pain [n=14]; complex regional pain syndrome [n=2]; and post-herpetic neuralgia [n=4]), who had been successfully treated with ......
Pain - Eur J Anaesthesiol 2010; 27: 169-73
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A retrospective effectiveness study of loss of resistance to air or saline for identification of the epidural space

Thu, 11 Feb 2010 00:00:00 GMT

trials comparing air to saline for loss of resistance (LOR) for identification of the epidural space have suggested that saline is more effective. These authors hypothesised that, in actual clinical practice, anaesthetists using their preferred technique would produce similar analgesic outcomes with either air or saline. BRP H3MethodsH3 PThe labour analgesia ......
Obstetrics - Anesth Analg 2010; 110: 558-63
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Obstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour

Thu, 11 Feb 2010 00:00:00 GMT

H3 PThe aim of this study was to compare the analgesic efficacy of remifentanil with meperidine and fentanyl in a patient-controlled setting (patient-controlled analgesia, PCA). BRP H3MethodsH3 PA total of 159 parturients were randomly assigned to receive remifentanil (n=52), meperidine (n=53) or fentanyl (n=54). Pain scores and an observer sedation scores were ......
Obstetrics - Br J Anaesth 2010; 104: 209-15
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The effect of dexmedetomidine on agitation during weaning of mechanical ventilation in critically ill patients

Thu, 11 Feb 2010 00:00:00 GMT

patients receiving opioids andor benzodiazepines are at high risk of developing agitation, particularly upon weaning towards extubation. This is often associated with an increased intubation time and length of stay in the intensive care unit and may cause long-term morbidity. Anxiety, fear and agitation are among the most common ......
Intensive Care - Anaesth Intensive Care 2010; 38: 82-90
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Ketamine, but not priming, improves intubating conditions during a propofol-rocuronium induction

Thu, 11 Feb 2010 00:00:00 GMT

authors carried out a study to investigate the effects of ketamine and priming as components of a propofol induction on intubating conditions and onset of neuromuscular block. BRP H3Methods H3 PThis prospective, randomised, double-blind study was performed in 120 American Society of Anesthesiologists (ASA) I-II patients who were assigned to one ......
Anaesthesia - Can J Anaesth 2010; 57: 113-9
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The impact of computerised physician order entry on prescribing practices in a cardiothoracic intensive care unit

Thu, 11 Feb 2010 00:00:00 GMT

authors carried out a prospective, time series, cross-sectional study to compare the quality of handwritten versus computerised prescriptions in a tertiary 25-bedded cardiothoracic intensive care unit. BRP H3Methods H3 PA total of 14,721 prescriptions for 613 patients were evaluated over three periods of investigation: 7 months before; and 5 and 12 ......
Anaesthesia - Anaesthesia 2009 Nov 4. [Epub ahead of print]
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Magnesium sulphate for treatment of tetanus in adults

Wed, 10 Feb 2010 00:00:00 GMT

H3 PAlthough reports suggest that magnesium sulphate alone may control muscle spasms, thereby avoiding sedation and mechanical ventilation in tetanus, this has not been confirmed. These authors examined the efficacy and safety of intravenous magnesium sulphate for the control of rigidity and spasms in adults with tetanus. BRP H3MethodsH3 PThe authors carried ......
Intensive Care - Anaesth Intensive Care 2010; 38: 185-9
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Systemic administration of lidocaine reduces morphine requirements and postoperative pain of patients undergoing thoracic surgery after propofol-remifentanil-based anaesthesia

Fri, 08 Jan 2010 00:00:00 GMT

H3 PRemifentanil is being increasingly used as an analgesic in fast-track surgery, but severe postoperative pain may occur occasionally. These authors evaluated the effects of systemic administration of lidocaine on postoperative pain and morphine requirements after propofol-remifentanil-based anaesthesia. BRP H3MethodsH3 PForty patients undergoing thoracic surgery were randomly assigned to lidocaine (33.0 �gkgmin) ......
Pain - Eur J Anaesthesiol 2010; 27: 41-6
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I.V. infusion of magnesium sulphate during spinal anaesthesia improves postoperative analgesia

Fri, 08 Jan 2010 00:00:00 GMT

H3 PThe authors carried out a randomised, double-blind, prospective study to evaluate the effect of intravenous (i.v.) infusion of magnesium sulphate during spinal anaesthesia on postoperative analgesia and postoperative analgesic requirements. BRP H3Methods H3 PForty patients undergoing total hip replacement arthroplasty under spinal anaesthesia were recruited to the study. After the induction ......
Pain - Br J Anaesth 2010; 104: 89-93
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