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You are in Home >> Intensive Care >> Respiratory >> Non-Invasive Vent >> Literature Review

Esteban et al. NIV after failed extubation. NEJM 2004.

Created: 16/5/2007

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Paper type

Randomised controlled trial

Reference

Esteban A, Frutos-Vivar F, Ferguson ND, Arabi Y, Apezteguia C et al.
Noninvasive positive-pressure ventilation for respiratory failure after extubation.
New England Journal of Medicine 2004; 350: 2542-2560

Major Finding
In patients who have respiratory failure post extubation noninvasive ventilation does not reduce reintubation rates and increases mortality.

Point for discussion:

If NIV is started earlier in those patients with respiratory failure post-extubation or selectively used in COPD patients, would re-intubation rates actually be reduced?

ArticleDate:20070516
SiteSection: Article