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ARDSnet: PEEP strategy. NEJM 2004

Created: 15/5/2007
Updated: 16/5/2007
 

Paper type

Randomised Controlled Trial

Reference

The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network.
Higher versus Lower Positive End-Expiratory Pressures in Patients with Acute respiratory Distress Syndrome.
N Eng J Med 2004;351;327-36.

Major Finding

There is no difference in outcome between "low PEEP" and "high PEEP" in patients ventilated with ARDS


Point for discussion:

Has this finally put the 'steroids in ARDS' debate to bed?

Major Finding

In patients with acute lung injury and ARDS who receive mechanical ventilation with lower tidal volumes and inspiratory pressures, raising PEEP to levels that exceed those used in our lower-PEEP strategy does not improve important clinical

Point for discussion:

What is the optimal level of PEEP to accompany low-tidal volume ventilation in the face of ARDS?
ArticleDate:20070515
SiteSection: Article
 
   
    
                                            
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