1. What are the main classes of local anaesthetics? - Give examples of each class. - How do they act? - What is your favourite local anaesthetic? - In what form is it present in a vial (i.e. what is its pH and state of ionisation?). - What happens when you inject a local anaesthetic? (pH and ionisation changes). - How are local anaesthetics metabolised?
2. What is flow-limited metabolism and what is capacity-limited metabolism?
3. Give examples of drug induction and inhibition.
4. What is etomidate? - Why is it painful on injection? - What does an ampule of etomidate contain? - What are the side-effects of etomidate?
ArticleDate:20060215
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